WebDec 3, 2015 · The relevance of RBM15 to blood diseases came to spot light when RBM15 was discovered to be involved in chromosome translocation t(1;22) in acute … WebRBM15, an RNA-binding protein, plays important roles in the growth and apoptosis of cells, especially blood cells through regulating multiple signal pathways such as Notch and Wnt. An increasing body of evidence has suggested that RBM15 may play a key function on the development of various blood diseases, such as acute/chronic myeloid leukemia and …
RBM15 Functions in Blood Diseases: Ingenta Connect
WebFeb 5, 2007 · To understand the role of the RBM15-MKL1 fusion protein in leukemia, we must understand the normal functions of RBM15 and MKL. Here, we show a role for Rbm15 in myelopoiesis. Rbm15 is expressed at highest levels in hematopoietic stem cells and at more moderate levels during myelopoiesis of murine cell lines and primary murine cells. WebRBM15. SECTIONS. TISSUE BRAIN SINGLE CELL TYPE TISSUE CELL TYPE PATHOLOGY DISEASE ... DISEASE. IMMUNE. BLOOD. SUBCELL. CELL LINE. ... RBM15. DISEASE. … flooring companies in bedford
Long non-coding RNA: Classification, biogenesis and functions in blood …
WebNov 16, 2007 · To study Rbm15 specifically in the regulation of HSC function, we generated Rbm15 conditional knockout mice using the Cre-LoxP system to overcome embryonic death observed with a ... (WBCs) were significantly decreased in the peripheral blood (PB) of Rbm15-deleted animals compared to controls (Rbm15-deleted: 5.33 ± 0.40 × 10 3 /uL ... WebOct 27, 2024 · Here we determined the clinical value, biological functions, and potential mechanisms of RBM15 in HCC. ... especially in advanced diseases . In recent years, ... WebRBM15. SECTIONS. TISSUE BRAIN SINGLE CELL TYPE TISSUE CELL TYPE PATHOLOGY DISEASE ... DISEASE. IMMUNE. BLOOD. SUBCELL. CELL LINE. ... RBM15. DISEASE. Disease overview. GENERAL INFORMATION i. Gene name i. RBM15: Gene description i. RNA binding motif protein 15: Predicted location i. Intracellular: HUMAN PROTEIN ATLAS … flooring companies humble tx