Ferroptotic 翻译
WebNov 19, 2024 · Regulation of Ferroptotic Cancer Cell Death by GPX4. 本选自cell 2013年老文章. 摘要:铁死亡是一种非凋亡细胞死亡形式,其关键调节因子尚不清楚。我们为12种 … WebDec 2, 2024 · Fig. 2: Core molecular machinery and signaling regulation of ferroptosis. Ferroptosis can occur through two major pathways, the extrinsic or transporter …
Ferroptotic 翻译
Did you know?
WebJan 21, 2024 · Ferroptotic response can be fine-tuned through various oxidative stress and antioxidant defense pathways, coupling with metabolism, gene transcription, and protein degradation machinery. Accordingly, a series of ferroptosis inducers or inhibitors targeting redox- or iron metabolism-related proteins or signal transduction have been developed. WebDespite the recent advances in cancer therapy, cancer chemoresistance looms large along with radioresistance, a major challenge in dire need of thorough and minute investigation. Not long ago, cancer cells were reported to have proven refractory to the ferroptotic cell death, a newly discovered form of regulated cell death (RCD), conspicuous enough to …
WebAstragaloside IV (AsIV), an active ingredient isolated from traditional Chinese medicine astragalus membranaceus, is beneficial to cardiovascular health. This study aimed to characterize the functional role of AsIV against adriamycin (ADR)-induced cardiomyopathy. Here, healthy rats were treated with … WebSep 11, 2024 · Additionally, a recent report showed that exogenous supplementation of iron led to an accelerated ferroptotic cell death in plants infected with the highly virulent Tobacco mosaic virus 24A+UPD (Macharia et al., 2024). However, the mechanisms leading to iron accumulation during ferroptotic cell death are still unknown in plants.
WebFerroptosis. Oxytosis/ferroptosis is a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides, and is genetically and biochemically distinct from other forms of regulated cell death such as apoptosis. [1] [2] Oxytosis/ferroptosis is initiated by the failure of the glutathione -dependent ... Web铁死亡(ferroptosis), 是一种调节性细胞死亡形式,其特征是铁依赖性脂质过氧化物积累到致死水平。. 这种不同于凋亡、坏死、自噬的新型细胞死亡方式,几乎以一己之力摧枯拉朽般地掀起研究狂潮,至今热度不减。. 今 …
WebGoogle 免费提供的这项服务可在简体中文和其他 100 多种语言之间即时翻译字词、短语和网页。
WebAug 9, 2024 · Understanding how cancer cells resist ferroptosis is a significant problem that impacts ongoing efforts to stimulate ferroptosis as a therapeutic strategy. We reported that prominin2 is induced by ferroptotic stimuli and functions to resist ferroptotic death. Although this finding has significant im … download font black ops oneWebFerroptosis is an exceptional metabolic process involving amino acids, lipids, NADPH, and microelements. However, cysteine depletion, GPX4 inactivation, and iron overload … claroty blogWebMar 29, 2024 · Ferroptosis is a novel type of cell death with distinct properties and recognizing functions involved in physical conditions or various diseases including … download font blow brushWebFeb 21, 2024 · In this study, we found that ferroptotic stress can help macrophages suppress intracellular bacteria by reversing the importation of ferrous iron into bacterial vacuoles via ferroportin and thereby inducing in situ ferroptosis-like bacterial death. Methods: A macrophage model of bacterial invasion was established to monitor dynamic … download font blooming elegant sans boldWebJun 7, 2024 · Excessive or deficient ferroptotic cell death is implicated in a growing list of physiological and pathophysiological processes, coupled to a dysregulated immune response. This review focuses on new discoveries related to how ferroptotic cells and their spilled contents shape innate and adaptive immunity in health and disease. download font brighly crushWeb2024-03-26报道,近日,中国医科大学的研究者们在Trends in Molecular Medicine杂志上发表了题为“Ferroptosis in Parkinson’s disease:glia–neuron crosstalk”的综述性文章,本综述研究了不同类型的胶质细胞在调节神经元铁性死亡中的可能作用。. 最后,研究者回顾了目前针 … download font blinker boldWebNov 2, 2024 · However, iron overload can damage the organism through a variety of mechanisms, including the induction of cell death. Ferroptosis is defined as an iron … download font bodoni bd bt